BLACK CUMIN SEED OIL
AND ECZEMA
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Eczema is a chronic skin inflammatory condition which causes extreme itchy skin rashes that results in severe discomfort to the affected individual. However, it is not a communicable or infectious skin disease.
The symptoms of eczema include unbearable itching, skin swelling, red rashes, blister formations and sometimes oozing occur through these blisters. Excessive itching diverts mental focus and causes sleep disturbance. [1] Eczema prevalence is quite high. Almost 30 percent Americans suffer from eczema. [2] Although the children and adolescents are mostly affected, the condition is even found in adults. Several medicines, including steroidal drugs, antihistamines are recommended to treat the condition, but the continuous application of these medications may provide some side effects. Therefore, medicinal products of natural origin is always a blessing for Eczema patients as it reduces the severity without any adverse effects. The scientific evidence supports the therapeutic benefits of black seed oil also reveals its effectiveness against eczema. [3] Why Is Black seed selected for treating Eczema?
The phytochemicals composition of black seed is primarily responsible for its efficiency to combat eczema and provide a choice of side effect free therapeutic option with improving skin condition. Thymoquinone, dithymoquinone, thymol, thymohydroquinone, alphahederin, carvacrol, nigellicine, nigellimine, and nigellidine are some bioactive ingredients present in the black seed which provide multiple dermatological (skin related) therapeutic benefits, including eczema controlling effect. Usually, the oil extracted from black seed is the most convenient way to obtain these benefits. [3] |
Mechanism of action of Black seed to combat Eczema
According to the clinical experts, the inflammatory response damages the corneal layer of the skin and hence the protective effect of the skin gets hampered. Therefore, the germs and allergens trigger the antibody production which causes the swelling of the skin. In addition, mutation of the gene due to oxidative stress causes a decreased rate of skin protein (filaggrin) synthesis, which imbalance fat content in the cutaneous layer and leads to a deficiency of skin moisture. [4] This dry scaly skin causes itching. [1] Following are some of the mechanism of action of black seed to combat eczema:
• Black seed possesses potential anti-oxidant property. The antioxidant property prevents abnormal genetic mutation by preventing DNA damage and thus maintain the protein synthesis and lipid content in the skin.
• The anti-inflammatory effect of black seed reduces white blood cells counts, bacterial growth and skin tissue destruction and benefits of this leads to prevent skin inflammatory condition and localized infections.
• Application of black seed accelerates wound healing process by uplifting fibroblast growth factor and transforming growth factor beta.
• The scope of skin infection development from eczema is minimized by black seed administration due to its wide range of antimicrobial effect, which prevents further infection.
• Black seed can control the hypersensitivity reaction by blocking the histamine release from the mast cell and further reduce the allergen-induced hyper-reactivity and control skin reactions including eczema related inflammation and itching.
• Black seed application improves epidermal-barrier functionality, which provides potential protection from a germ or other foreign objects, which trigger an inflammatory response of the skin and prevents eczema.
• Black seed also improves the moisture content of the skin and controls itching by removing dryness.
• In addition, combination therapy of the black seed oil with other therapeutic agents can also improve the potentiality of the medication by improving permeability of the skin. [3]
According to the clinical experts, the inflammatory response damages the corneal layer of the skin and hence the protective effect of the skin gets hampered. Therefore, the germs and allergens trigger the antibody production which causes the swelling of the skin. In addition, mutation of the gene due to oxidative stress causes a decreased rate of skin protein (filaggrin) synthesis, which imbalance fat content in the cutaneous layer and leads to a deficiency of skin moisture. [4] This dry scaly skin causes itching. [1] Following are some of the mechanism of action of black seed to combat eczema:
• Black seed possesses potential anti-oxidant property. The antioxidant property prevents abnormal genetic mutation by preventing DNA damage and thus maintain the protein synthesis and lipid content in the skin.
• The anti-inflammatory effect of black seed reduces white blood cells counts, bacterial growth and skin tissue destruction and benefits of this leads to prevent skin inflammatory condition and localized infections.
• Application of black seed accelerates wound healing process by uplifting fibroblast growth factor and transforming growth factor beta.
• The scope of skin infection development from eczema is minimized by black seed administration due to its wide range of antimicrobial effect, which prevents further infection.
• Black seed can control the hypersensitivity reaction by blocking the histamine release from the mast cell and further reduce the allergen-induced hyper-reactivity and control skin reactions including eczema related inflammation and itching.
• Black seed application improves epidermal-barrier functionality, which provides potential protection from a germ or other foreign objects, which trigger an inflammatory response of the skin and prevents eczema.
• Black seed also improves the moisture content of the skin and controls itching by removing dryness.
• In addition, combination therapy of the black seed oil with other therapeutic agents can also improve the potentiality of the medication by improving permeability of the skin. [3]
Scientific evidence supports the Black seed oil efficacy against eczema
There are research evidence and clinical trial data that support the efficacy of black seed against eczema.
A double-blinded, randomized, controlled clinical trial was conducted to check the efficacy of black seed on 60 patients having hand eczema between 18-60 years of age. Eucerin and Betamethasone were the two comparator medicines selected against black seed in this trial. Eucerin is a popular dermatological brand for skin care and Betamethasone is a steroid medication for treating eczema with varied steroidal side effects.
The test result showed that black seed is more effective to treat eczema than Eucerin; whereas black seed and Betamethasone have similar efficacy to treat eczema. The author of this study concluded that black seed can able to treat severe eczema and improve the quality of life of the patients. [5]
There are research evidence and clinical trial data that support the efficacy of black seed against eczema.
A double-blinded, randomized, controlled clinical trial was conducted to check the efficacy of black seed on 60 patients having hand eczema between 18-60 years of age. Eucerin and Betamethasone were the two comparator medicines selected against black seed in this trial. Eucerin is a popular dermatological brand for skin care and Betamethasone is a steroid medication for treating eczema with varied steroidal side effects.
The test result showed that black seed is more effective to treat eczema than Eucerin; whereas black seed and Betamethasone have similar efficacy to treat eczema. The author of this study concluded that black seed can able to treat severe eczema and improve the quality of life of the patients. [5]
-Another animal study model showed that combination of black seed oil in 5% v/v with lipophilic drug-carvedilol increases the percutaneous absorption of the drug. The black seed oil can extort lipids from stratum corneum layer of the skin and untie the hydrogen bonds between ceramides with consequent fluidization of the lipid bilayer. [3]
Direction to get the effective result
The best result can be possible by following proper directions and techniques in administering and/or applying black seed therapy to treat Eczema:
• The oil of black seed has a good skin permeability and can be directly applied to the Eczema affected area. The black seed oil gives great therapeutic benefit when applied alone but an excess of the amount can cause skin irritation.
• Experts recommended sufficient black seed oil mixed with honey is a better option to treat eczema. Honey acts as a natural moisturizer in this mixture. Eczema affected patients can ingest this mixer because honey makes it palatable due to its sweet taste. The mixture can even be applied to eczema affected area to impart desired therapeutic effect. [6]
• Topical application of black seed oil and apple cider vinegar provide a better result. The apple cider vinegar is a good source of bioflavonoids, vitamins, minerals and antioxidant. These properties improve skin quality and provide a protective effect. It is recommended to dilute this mixture of black seed oil and apple cider vinegar with distilled water to avoid skin irritation. After 15-20 min of application, this mixture can be washed out.
• Black seed oil when combined with lemon juice gives better protection from microbial attack. However, the quantity of lemon juice should be less, otherwise, it may irritate the skin. Wash it after 15-20 minutes of topical application.[7]
Direction to get the effective result
The best result can be possible by following proper directions and techniques in administering and/or applying black seed therapy to treat Eczema:
• The oil of black seed has a good skin permeability and can be directly applied to the Eczema affected area. The black seed oil gives great therapeutic benefit when applied alone but an excess of the amount can cause skin irritation.
• Experts recommended sufficient black seed oil mixed with honey is a better option to treat eczema. Honey acts as a natural moisturizer in this mixture. Eczema affected patients can ingest this mixer because honey makes it palatable due to its sweet taste. The mixture can even be applied to eczema affected area to impart desired therapeutic effect. [6]
• Topical application of black seed oil and apple cider vinegar provide a better result. The apple cider vinegar is a good source of bioflavonoids, vitamins, minerals and antioxidant. These properties improve skin quality and provide a protective effect. It is recommended to dilute this mixture of black seed oil and apple cider vinegar with distilled water to avoid skin irritation. After 15-20 min of application, this mixture can be washed out.
• Black seed oil when combined with lemon juice gives better protection from microbial attack. However, the quantity of lemon juice should be less, otherwise, it may irritate the skin. Wash it after 15-20 minutes of topical application.[7]
Which Black Seed Oil Do I Use?
I highly recommend this oil. I am so positive you will love my favorite oil too.
I highly recommend this oil. I am so positive you will love my favorite oil too.
TESTIMONY FROM YOUTUBE.COM
Blessings, and humble gratitude beautiful Mother! Thank you for this information. I take my BSO in the morning on an empty tummy, and I've suffered from eczema and psoriasis really badly all year round, since I was a baby. Taking my BSO has smoothed my skin completely, including dry patches, that were inflamed, and my rough hands and feet. BSO has even ceased all acne breakouts for me. Never tried it externally, but taking it orally has helped me tremendously! Please keep sharing!
Blessings, and humble gratitude beautiful Mother! Thank you for this information. I take my BSO in the morning on an empty tummy, and I've suffered from eczema and psoriasis really badly all year round, since I was a baby. Taking my BSO has smoothed my skin completely, including dry patches, that were inflamed, and my rough hands and feet. BSO has even ceased all acne breakouts for me. Never tried it externally, but taking it orally has helped me tremendously! Please keep sharing!
Some precautionary measure
• Always purchase organic black seed oil from authentic supplier to avoid adulteration.
• Skin patch test needs to be performed before direct application of black seed oil on eczema affected area to prevent unwanted skin reaction.
• In case of pregnancy, advice from medical professionals for using black seed oil is suggested. [7]
References
• Always purchase organic black seed oil from authentic supplier to avoid adulteration.
• Skin patch test needs to be performed before direct application of black seed oil on eczema affected area to prevent unwanted skin reaction.
• In case of pregnancy, advice from medical professionals for using black seed oil is suggested. [7]
References
- Eczema: Overview; Retrieved from https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0072583/
- Eczema (Atopic Dermatitis); Retrieved from https://www.niaid.nih.gov/diseases-conditions/eczema-atopic-dermatitis
- Salih H.M.Aljabre, Omar M.Alakloby, Mohammad A.Randhawa. Dermatological effects of Nigella sativa. Journal of Dermatology & Dermatologic Surgery. Volume 19, Issue 2, July 2015, Pages 92-98. Retrieved from https://www.sciencedirect.com/science/article/pii/S2352241015000286
- N. Sivaranjani, S. Venkata Rao, G. Rajeev. Role of Reactive Oxygen Species and Antioxidants in Atopic Dermatitis. J Clin Diagn Res. 2013 Dec; 7(12): 2683–2685. Published online 2013 Dec 15. doi: 10.7860/JCDR/2013/6635.3732 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919411/
- M. Yousefi , B. Barikbin , M. Kamalinejad , E. Abolhasani , A. Ebadi, S. Younespour , M. Manouchehrian, S. Hejazi; Comparison of therapeutic effect of topical Nigella with Betamethasone and Eucerin in hand eczema; J Eur Acad Dermatol Venereol. 2013 Dec;27(12):1498-504. doi: 10.1111/jdv.12033. Epub 2012 Dec 1; About Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/23198836
- Healing Eczema Naturally: The Role of Black Seed Oil. Retrieved from https://www.curezone.org/forums/am.asp?i=7470
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