YOUR 1 STOP CENTER
  • HOME
  • Store
    • Herbal Store
  • HOW TO TAKE
    • Dosage for Black Seed Oil and Seeds
  • DOSAGES
    • Nigella Sativa – Scientific Rationale Related to its Therapeutic Effects
  • Pets
  • Cancer
    • Black Cumin is Breast Cancer's Worse Enemy
    • Cancer Diet - Healthy Eating for Cancer Patients
    • Chemotherapy May Cause Tumors to Spread like Wildfires
    • Is There a Cure for Pancreatic Cancer Using Black Cumin
    • Natural Remedies for Skin Cancer - 1 Being Nigella Sativa
    • Nigella Sativa Allieviates Bone Cancer
    • Nigella sativa (Black seeds) anti-leukemic Effects – A Safer Alternative
    • RESEARCH SHOWS THAT CANCER RATES WILL RISE DRASTICALLY OVER THE COMING YEARS
    • The Anti-Cancer Healing Protocol >
      • The Anti-Cancer Healing Protocol - Page 2
  • FIBRO
    • Fibromyalgia: signs, symptoms, and remedies for this debilitating condition
    • Nigella Sativa, CBD, and More: Solutions for Fibromyalgia
  • CBD AND NIGELLA SATIVA
    • Cannabis Sativa vs Nigella Sativa - Which One is Best
    • Nigella sativa: the cousin of cannabis sativa with a powerful story to tell
  • VIDEOS
    • VIDEO DIRECTORY
  • Surviving Through the COVID-19 Pandemic
  • Top 20 Reasons to use Black Cumin Oil and Capsules
  • Articles
    • Black Cumin Seed Oil Benefits -
    • Black Seeds Increase Semen Quality in Men
    • The Latest in Health Trends: Black Seed Oil
    • The Many Health Benfits of Honey - The Blessed Gift
  • Articles 2
    • BLACK SEED OIL IS BETTER THAN TYLENOL FOR ARTHRITIS RELIEF
    • Can You Lose Weight with Nigella Sativa
    • Migraines - Headaches - 12 Remedies with Pictures
    • My Protocol for Dementia Recovery
    • The Amazing Health Benefits of Pure Yemeni Sidr Honey - The World's Best Honey
    • The Best Herbal Teas for Cancer and 1 is Nigella Sativa
  • PRIVACY POLICY - GDPR COMPLIANT
  • Contact
  • About
  • Healthy Articles
  • Nigella Sativa Online Courses - Part 1
    • Nigella Sativa Online Courses - Part 2
    • Nigella Sativa Online Courses - Part 3
  • Untitled
  • Store
  • PCOS and Nigella Sativa
  • Childhood Epilepsy
  • Natural Diuretics
  • New Page
  • Nigella Sativa Respiratory Illness
  • Healing Effect on Sarcoidosis
  • EBOOKS
  • Cardiovascular Disease
  • Nigella sativa and Honey Coronavirus
  • Depression and COVID19
  • 12
  • 15% Off Coupon - Perfect Press Black Seed Oil
  • Consultation
  • How to Use Nigella Sativa
  • How Contagious is Leprosy
  • Kidney Cancer
  • Kidney Failure - Stage 5
  • FREE EXPLORATORY PHONE CALL
  • New Page
  • Supporting Human Health - The Immunomodulator
Picture
Picture
Picture

Nigella sativa: the cousin of cannabis sativa with a powerful story to tell

REVIEWED BY DR. NITA SHARMA DAS, PHD, ND, PHDHM, B PHARM. August 22, 2018
THIS ARTICLE IS COPYRIGHTED FOR NIGELLA--SATIVA.COM ONLY.  ALL RIGHTS RESERVED.

Since 1940, the United States along with many other countries banned Cannabis sativa, popularly known as Marijuana due to its addictive nature.

∆9-tetrahydrocannabinol is one of the major psychoactive constituent present in Cannabis responsible drug abuse.

However, cannabinoids is one of the principal constituent of Cannabis has several therapeutic benefits to treat numerous diseases, which include anorexia, emesis, pain, inflammation, multiple sclerosis, neurodegenerative disorders (Parkinson's disease, Huntington's disease, Tourette's syndrome, Alzheimer's disease), epilepsy, glaucoma, osteoporosis, schizophrenia, cardiovascular disorders, cancer, obesity, and metabolic syndrome-related disorders, etc. [1]

Therefore, banning of cannabis was a huge shrinkage of therapeutic benefits  in the medicinal plant Kingdome. But medicinal plant researchers got a new alternative of Cannabis sativa and i.e. Nigella sativa.  Though researchers continuously working on Cannabis sativa to lessen the side effect burdens of this medicinal plant to convalesce its acceptance in therapeutic application.   
 
Nigella sativa is considered can be considered a cousin of the Cannabis sativa, as both of them are seed-bearing plant and belongs to the same species, sativa. [2] It is notable Nigella sativa is already a potential medicinal herb in traditional medicine and reorganization in Holy Bible make this herbal ingredient as ' 'blessed seed'. [3]

While nigella sativa goes by many names depending on where in the world it's being classified–black cumin, Roman coriander, and "Kalonji" in Hindi-Urdu representing just a few of its more common designations–the benefits of nigella sativa are ubiquitous, irrespective of what people choose to call it.
 
Both the seeds and the oil of nigella sativa are so highly renowned in ancient folklore that they've earned designations as both "superfoods" and herbal medicines. In Islamic literature, for instance, nigella sativa is regarded as the world's preeminent healing food, the Prophet Muhammad likening it to "a cure for every disease except death."(4)

The three 'thymos' that render nigella sativa a healing food of the highest order

Hailing from the same botanical family as cannabis sativa, Nigella sativa bears many similar properties, both from a nutritive and remedial standpoint. For one, it's loaded with essential fatty acids like linoleic acid, as well as more than a dozen essential amino acids, a slew of trace minerals, numerous cholesterol-lowering phytosterols, and carotene, a type of plant pigment that functions as a nutrient precursor to vitamin A.[4, 5, 6,7]
 
There are also three additional phytochemical constituents that make Nigella sativa particularly unique: thymoquinone (TQ), thymohydroquinone (THQ), and thymol.All three of these natural compounds are found in the essential oil of Nigella sativa, and each one lends to the herb's incredible ability to supplant conventional pharmaceuticals, including popular antibiotics and many antiviral and antifungal drugs. [4]
 
Thymoquinone is considered to be the primary active ingredient in Nigella sativa, probably because it's the most studied of its known constituents. Research dating back to the 1960s suggests that thymoquinone bears powerful antioxidant, anti-inflammatory, hepatoprotective, and anti-cancer properties.

Thymoquinone has also been shown to positively counteract conditions like asthma, hypertension, headaches, diabetes, influenza, and eczema, as well as viral infections that can lead to inflammation of the brain and spinal cord. And who could forget about its powerful anti-fungal properties that work to keep harmful dermatophytes and yeasts at bay. [8]
 
The antioxidant protection of thymoquinone is particularly noteworthy in that it scavenges not only free radicals but also superoxide radicals–meaning it helps to preserve glutathione peroxidase and glutathione S transferase, the two enzymes that aid the "master" antioxidant glutathione in supporting longevity and detoxification throughout the body. [9]
 
With regards to cancer, thymoquinone further helps to regulate the body's natural anti-cancer defense system. Though research in this area is ongoing, existing evidence suggests that thymoquinone works to induce apoptosis, or cell suicide, in cancer cells. [10] Thymoquinone also controls the Akt pathway, which plays a key role in cell proliferation and survival, cell motility, and angiogenesis.[11]
 
Thymohydroquinone functions similarly to thymoquinone, with the added benefit that it's one of the most potent acetylcholinesterase (AChE) inhibitors in existence. AChE inhibitors of the pharmaceutical variety are often used to treat cognitive abnormalities such as dementia and Alzheimer's disease, as well as autism, glaucoma, neurodegenerative disease, schizophrenia, postural tachycardia syndrome, and Parkinson's disease, suggesting that thymohydroquinone could be a powerful natural alternative.[12, 13]
 
Thymol is the same active monoterpene in the thyme herb that's commonly used in natural medicine to kill tuberculosis and other viral-based conditions. [14] Thymol is also a powerful natural disinfectant and pesticide, which is why it's often used in natural household sprays and garden products in lieu of its various synthetic counterparts, many of which are known to be harmful to animals and humans.


Nigella and cannabis: a one-two punch against cancer and other diseases

One of the most promising applications for Nigella sativa is as an anti-cancer food, both in prevention and treatment. Its three "thymos" work in synergistic cooperation to stop cancer cells from growing and spreading, while simultaneously triggering their programmed cell death. Consuming Nigella sativa seeds and oil can further aid in promoting cell cycle arrest while blocking cancer cells from replicating and forming into secondary malignant growths.
 
"The anti-tumor effects of thymoquinone have ... been investigated in tumor xenograft mice models for colon, prostate, pancreatic and lung cancer," one study explains. [14] Animal research data supported that a combination of conventional chemotherapeutic medicine with thymoquinone has a potent therapeutic effect and creates less toxicity load in the physiological system.   "The combination of thymoquinone and conventional chemotherapeutic drugs could produce a greater therapeutic effect as well as reduce the toxicity of the latter."[15]
 
What's more, the prospect of combining nigella sativa with its cannabis Sativa cousin suggests even further supportive benefits against cancer. The many unique cannabinoid constituents present in cannabis sativa already have the potential to replace practically every synthetic drug in the medicine cabinet, and research suggests that using the whole plant in conjunction with Nigella sativa could produce even greater benefits.

Another common finding between Cannabis sativa and Nigella sativa is both of these herbal plants have anticancer property. Cannabinoids present in Cannabis sativa including tetrahydrocannabinol possess anticancer property, whereas thymoquinone along with other biologically active constituents present in Nigella sativa also has antitumor activity. [16, 17]
Experts recommended a combination of this herbal agent with other conventional anticancer drugs can reduce tumor development, progression, and metastasis. [18, 19]
 
Whole-plant cannabis sativa has already been shown to produce what's known as an "entourage" effect throughout the body, meaning its many diverse constituents work in almost supernatural harmony with one another to support comprehensive health and well-being.

Combined with Nigella sativa, this entourage effect expands even further in ways that modern science is only just beginning to uncover– and future research data assists to establish the safety profile and estimate the correct dose of the combination therapy of these two sativa species.

References

  1. Natalya M. Kogan, Raphael Mechoulam. Cannabinoids in health and disease.  Dialogues Clin Neurosci. 2007 Dec; 9(4): 413–430.  Online available https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202504/
  2. Sativum, https://en.wikipedia.org/wiki/Sativum
  3. Hala Gali-Muhtasib, Regine Schhneider-stock, Nahed El-Najjar. The medicinal potential of black seed (Nigella sativa) and its components. DOI: 10.1016/S1572-557X(05)02008-8. Online available at https://www.researchgate.net/publication/223809080_
  4. Safia A. AlAttas, Fat’heya M. Zahran, Shereen A. Turkistany. Nigella sativa and its active constituent thymoquinone in oral health. Saudi Med J. 2016 Mar; 37(3): 235–244. doi: 10.15537/smj.2016.3.13006. Online available at  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800885/
  5. House JD, Neufeld J, Leson G.  Evaluating the quality of protein from hemp seed (Cannabis sativa L.) products through the use of the protein digestibility-corrected amino acid score method. J Agric Food Chem. 2010 Nov 24;58(22):11801-7. doi: 10.1021/jf102636b. Epub 2010 Oct 26. Online available  https://www.ncbi.nlm.nih.gov/pubmed/20977230
  6. Helga Mölleken, Roland R. Theimer . Survey of minor fatty acids in Cannabis sativa L. fruits of various origins. Online available  http://www.internationalhempassociation.org/jiha/jiha4107.html
  7. Md. Atiqual Islam, Beom-Gyum Jeong, Jiyoung Jung, Jiyeon Chun. Phytosterol Determination and Method Validation for Selected Nuts and Seeds. DOI: 10.1007/s12161-017-0877-3. Online available at https://www.researchgate.net/publication/315945196_Phytosterol_Determination_and_Method_Validation_for_Selected_Nuts_and_Seeds
  8. Mohannad Khader, Peter M Eckl. Thymoquinone: an emerging natural drug with a wide range of medical applications. Iran J Basic Med Sci. 2014 Dec; 17(12): 950–957. Online available at  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387230/
  9. Woo CC, Kumar AP, Sethi G, Tan KH. Thymoquinone: potential cure for inflammatory disorders and cancer. Biochem Pharmacol. 2012 Feb 15;83(4):443-51. doi: 10.1016/j.bcp.2011.09.029. Epub 2011 Oct 10.  Online available at https://www.ncbi.nlm.nih.gov/pubmed/22005518
  10. Md Asaduzzaman Khan, Han-chun Chen, Mousumi Tania, Dian-zheng Zhang. Anticancer Activities of Nigella Sativa (Black Cumin). Afr J Tradit Complement Altern Med. 2011; 8(5 Suppl): 226–232. Online available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252704/
  11. Joseph R Testa, Philip N Tsichlis. AKT signaling in normal and malignant cells. Oncogene volume24, pages7391–7393 (14 November 2005).  Online available at https://www.nature.com/articles/1209100?foxtrotcallback=true
  12. Jukic M, Politeo O, Maksimovic M, Milos M, Milos M. In vitro acetylcholinesterase inhibitory properties of thymol, carvacrol and their derivatives thymoquinone and thymohydroquinone. Phytother Res. 2007 Mar;21(3):259-61.  Online available at https://www.ncbi.nlm.nih.gov/pubmed/17186491
  13. Mohammad Reza Khazdair. The Protective Effects of Nigella sativa and Its Constituents on Induced Neurotoxicity. J Toxicol. 2015; 2015: 841823. Published online 2015 Oct 29. doi: 10.1155/2015/841823.  Online available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641935/
  14. Hongxia Niu, Chao Ma, Peng Cui, Wanliang Shi, Shuo Zhang, Jie Feng et al. Identification of drug candidates that enhance pyrazinamide activity from a clinical compound library. Emerging Microbes & Infections volume6, pagee27 (2017) Online available at https://www.nature.com/articles/emi201723
  15. Fatemeh Sheikhbahaei, et. al. Protective Effects of Thymoquinone against Methotrexate-Induced Germ Cell Apoptosis in Male Mice. Int J Fertil Steril. 2016 Jan-Mar; 9(4): 541–547. Published online 2015 Dec 23. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793176/
  16. G. Velasco, C. Sánchez, M. Guzmán. Anticancer mechanisms of cannabinoids. Curr Oncol. 2016 Mar; 23(Suppl 2): S23–S32. Online available at  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791144/
  17. ELSAYED I. SALIM. Cancer chemopreventive potential of volatile oil from black cumin seeds, Nigella sativa L., in a rat multi-organ carcinogenesis bioassay. Oncol Lett. 2010 Sep; 1(5): 913–924. Published online 2010 Sep 1. doi: 10.3892/ol_00000162. Online available at  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436209/
  18. Amin F. Majdalawieh, Muneera W. Fayyad. Recent advances on the anti-cancer properties of Nigella sativa, a widely used food additive. J Ayurveda Integr Med. 2016 Jul-Sep; 7(3): 173–180. Published online 2016 Sep 17. doi: 10.1016/j.jaim.2016.07.004. Online available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052360/
  19. G. Velasco, C. Sánchez, M. Guzmán. Anticancer mechanisms of cannabinoids. Curr Oncol. 2016 Mar; 23(Suppl 2): S23–S32. Published online 2016 Mar 16. doi: 10.3747/co.23.3080. Online available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791144/

    SIGN UP FOR MY FREE NEWSLETTER

Subscribe to Newsletter

ABOUT US
We at Nigella Sativa, ie BSE Imports/Exports believe that natural medicine and especially black seed oil can reverse all disease when taken properly with diet and exercise.

We have many experts here which include some of the best doctors and nurses in the field of Nigella Sativa also.  I have been helping people for more than 10 years be wll naturally and we hope this information will help you also.

Picture
Amazon Affiliate Disclosure

https://www.nigellasativacenter.com  is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for website owners to earn advertising fees by advertising and linking to amazon(.com, .co.uk, .ca etc) and any other website that may be affiliated with Amazon Service LLC Associates Program. 

“Amazon and the Amazon logo are trademarks of Amazon.com, Inc. or its affiliates.” 
Picture

Disclaimer: The information on this page and on this website has not been evaluated by the FDA. We do not diagnose, treat, cure or prevent illness or disease - instead, we try to help people learn how to do so themselves. Anyone who believes they have a serious medical condition or health issue should seek diagnoses from a qualified medical professional before making any decisions on how to best address their health.   Furthermore, anyone contemplating using any products or information on this website must accept such use as experimental and voluntary. No claims are made regarding the therapeutic use of the products or information on this website and all products featured or sold on this website must be considered nutritional supplements only. -
Copyright Protected - Nigella Sativa.com - 2018-2020 - All Rights Reserved -  Any infringe on our copyright will be prosecuted to the fullest extent of the law.
  • HOME
  • Store
    • Herbal Store
  • HOW TO TAKE
    • Dosage for Black Seed Oil and Seeds
  • DOSAGES
    • Nigella Sativa – Scientific Rationale Related to its Therapeutic Effects
  • Pets
  • Cancer
    • Black Cumin is Breast Cancer's Worse Enemy
    • Cancer Diet - Healthy Eating for Cancer Patients
    • Chemotherapy May Cause Tumors to Spread like Wildfires
    • Is There a Cure for Pancreatic Cancer Using Black Cumin
    • Natural Remedies for Skin Cancer - 1 Being Nigella Sativa
    • Nigella Sativa Allieviates Bone Cancer
    • Nigella sativa (Black seeds) anti-leukemic Effects – A Safer Alternative
    • RESEARCH SHOWS THAT CANCER RATES WILL RISE DRASTICALLY OVER THE COMING YEARS
    • The Anti-Cancer Healing Protocol >
      • The Anti-Cancer Healing Protocol - Page 2
  • FIBRO
    • Fibromyalgia: signs, symptoms, and remedies for this debilitating condition
    • Nigella Sativa, CBD, and More: Solutions for Fibromyalgia
  • CBD AND NIGELLA SATIVA
    • Cannabis Sativa vs Nigella Sativa - Which One is Best
    • Nigella sativa: the cousin of cannabis sativa with a powerful story to tell
  • VIDEOS
    • VIDEO DIRECTORY
  • Surviving Through the COVID-19 Pandemic
  • Top 20 Reasons to use Black Cumin Oil and Capsules
  • Articles
    • Black Cumin Seed Oil Benefits -
    • Black Seeds Increase Semen Quality in Men
    • The Latest in Health Trends: Black Seed Oil
    • The Many Health Benfits of Honey - The Blessed Gift
  • Articles 2
    • BLACK SEED OIL IS BETTER THAN TYLENOL FOR ARTHRITIS RELIEF
    • Can You Lose Weight with Nigella Sativa
    • Migraines - Headaches - 12 Remedies with Pictures
    • My Protocol for Dementia Recovery
    • The Amazing Health Benefits of Pure Yemeni Sidr Honey - The World's Best Honey
    • The Best Herbal Teas for Cancer and 1 is Nigella Sativa
  • PRIVACY POLICY - GDPR COMPLIANT
  • Contact
  • About
  • Healthy Articles
  • Nigella Sativa Online Courses - Part 1
    • Nigella Sativa Online Courses - Part 2
    • Nigella Sativa Online Courses - Part 3
  • Untitled
  • Store
  • PCOS and Nigella Sativa
  • Childhood Epilepsy
  • Natural Diuretics
  • New Page
  • Nigella Sativa Respiratory Illness
  • Healing Effect on Sarcoidosis
  • EBOOKS
  • Cardiovascular Disease
  • Nigella sativa and Honey Coronavirus
  • Depression and COVID19
  • 12
  • 15% Off Coupon - Perfect Press Black Seed Oil
  • Consultation
  • How to Use Nigella Sativa
  • How Contagious is Leprosy
  • Kidney Cancer
  • Kidney Failure - Stage 5
  • FREE EXPLORATORY PHONE CALL
  • New Page
  • Supporting Human Health - The Immunomodulator