RESEARCH ON WHY YOU SHOULD HEAT NIGELLA SATIVA SEEDS
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Many many years ago I wrote and talked much on the proper heating for black seeds (Nigella sativa) I was thrilled to see my write Dr. Nas mention and resource on this topic when talking on Lymphoma Cancers.
The article is titled: Anticancer activity of Nigella sativa (black seed) and its relationship with the thermal processing and quinone composition of the seed. You can see I wrote a blog post on this a long time ago. |
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AbstractThe traditional preparation process of Nigella sativa (NS) oil starts with roasting of the seeds, an allegedly unnecessary step that was never skipped. The aims of this study were to investigate the role and boundaries of thermal processing of NS seeds in the preparation of therapeutic extracts and to elucidate the underlying mechanism. NS extracts obtained by various seed thermal processing methods were investigated in vitro for their antiproliferative activity in mouse colon carcinoma (MC38) cells and for their thymoquinone content. The effect of the different methods of thermal processing on the ability of the obtained NS oil to inhibit the nuclear factor kappa B (NF-κB) pathway was then investigated in Hodgkin’s lymphoma (L428) cells.
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The different thermal processing protocols yielded three distinct patterns: heating the NS seeds to 50°C, 100°C, or 150°C produced oil with a strong ability to inhibit tumor cell growth; no heating or heating to 25°C had a mild antiproliferative effect; and heating to 200°C or 250°C had no effect. Similar patterns were obtained for the thymoquinone content of the corresponding oils, which showed an excellent correlation with the antiproliferative data. It is proposed that there is an oxidative transition mechanism between quinones after controlled thermal processing of the seeds. While NS oil from heated seeds delayed the expression of NF-κB transcription, non-heated seeds resulted in only 50% inhibition. The data indicate that controlled thermal processing of NS seeds (at 50°C–150°C) produces significantly higher anticancer activity associated with a higher thymoquinone oil content, and inhibits the NF-κB signaling pathway.
RESOURCE
- Riad Agbaria, Adi Gabarin, Arik Dahan, Shimon Ben-Shabat. Anticancer activity of Nigella sativa (black seed) and its relationship with the thermal processing and quinone composition of the seed. Drug Des Devel Ther. 2015; 9: 3119–3124. Published online 2015 Jun 18. doi: 10.2147/DDDT.S82938. https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4476428/
WHICH EGYPTIAN BLACK SEEDS DO I RECOMEND?
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