LEARN HOW TO REVERSE MULTIPLE SCLEROSIS FAST
WITH NIGELLA SATIVA
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In 1866, Charcot and Vulpain have first described this nervous system disorder as Multiple Sclerosis, but unfortunately, no cure has yet been discovered. Almost 2.5 million people all over the world face the recurrence of demyelination of the central nervous system due to Multiple Sclerosis. The chronic nature of this disease often causes disability. [1]
In modern days, alternative therapy is gradually taking the center stage, because of evident research findings supporting that alternative therapy is cost-effective, mostly side-effect free and have a wide range of health benefits. [1] Among these several alternative therapies, herbal regimens for Multiple Sclerosis treatment get special attention to researchers.
Researchers listed out some of the herbal medicines, which initially proved to be effective against Multiple Sclerosis. [2] Nigella sativa is one of the promising herbal drugs for Multiple Sclerosis with its neuroprotective, anti-inflammatory and anti-oxidative effects. [3] Before we discuss more the role of Nigella sativa in prevention and relapse of Multiple Sclerosis, it is imperative to know about Multiple Sclerosis.
In modern days, alternative therapy is gradually taking the center stage, because of evident research findings supporting that alternative therapy is cost-effective, mostly side-effect free and have a wide range of health benefits. [1] Among these several alternative therapies, herbal regimens for Multiple Sclerosis treatment get special attention to researchers.
Researchers listed out some of the herbal medicines, which initially proved to be effective against Multiple Sclerosis. [2] Nigella sativa is one of the promising herbal drugs for Multiple Sclerosis with its neuroprotective, anti-inflammatory and anti-oxidative effects. [3] Before we discuss more the role of Nigella sativa in prevention and relapse of Multiple Sclerosis, it is imperative to know about Multiple Sclerosis.
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Overview of Multiple Sclerosis
Our nervous system is covered with a myelin protein, which is also known as Myelin sheath. This myelin sheath helps to transport information from one nerve to another through transferring signaling. The Multiple Sclerosis causes the neurodegenerative condition. Demyelination is the primary pathology responsible to obstruct transferring of the nerve signals or result complete blockage. The metabolic disorder induced by autoimmune disorder gradually causes neurodegeneration. Due to the nervous system impacted by the immune system, immunoglobulin G (IgG) raises up in the cerebrospinal fluid. |
The autoimmune immunoglobulin G has anti-myelin basic protein (anti-MBP) activity which causes demethylation. In addition, autoimmune condition influence inflammatory condition in the T cell of the white matter of central nervous system.
Thus, demyelination and inflammation gradually destroy oligodendrocytes, which is present in the axon of the nervous tissue and plaque is formed. [1] Moreover, researchers also expected that oxidative stress also induces pathological changes in the development of Multiple Sclerosis. [3]
In some Multiple Sclerosis (MS) patients, the degree of severity is less as oligodendrocytes are partially destroyed, and thus remyelination is possible. However, complete destruction of oligodendrocytes causes total demyelination. [1
]
Most of the MS patients identified the Relapse-remitting type of Multiple Sclerosis and usually familiar with a new set of symptoms in every relapse attacks, and gradually symptoms become prominent. However, primary progressive and secondary progressive multiple sclerosis are the other two types which are classified under MS category.
The patients usually have weakness in the limb, sensory disturbance, pricking sensation in the limb and truck, body balancing problem, clumsiness, curvature in the neck, vision disturbance due to optic nerve inflammation and demyelination.
The available conventional therapy reduces the inflammation in the nervous system and delays the demyelination along with slowing down the symptomatic expression. But the synthetic medication has their own side effects, which also interfere the quality of life of the patients. [1]
Thus, demyelination and inflammation gradually destroy oligodendrocytes, which is present in the axon of the nervous tissue and plaque is formed. [1] Moreover, researchers also expected that oxidative stress also induces pathological changes in the development of Multiple Sclerosis. [3]
In some Multiple Sclerosis (MS) patients, the degree of severity is less as oligodendrocytes are partially destroyed, and thus remyelination is possible. However, complete destruction of oligodendrocytes causes total demyelination. [1
]
Most of the MS patients identified the Relapse-remitting type of Multiple Sclerosis and usually familiar with a new set of symptoms in every relapse attacks, and gradually symptoms become prominent. However, primary progressive and secondary progressive multiple sclerosis are the other two types which are classified under MS category.
The patients usually have weakness in the limb, sensory disturbance, pricking sensation in the limb and truck, body balancing problem, clumsiness, curvature in the neck, vision disturbance due to optic nerve inflammation and demyelination.
The available conventional therapy reduces the inflammation in the nervous system and delays the demyelination along with slowing down the symptomatic expression. But the synthetic medication has their own side effects, which also interfere the quality of life of the patients. [1]
Multiple Sclerosis Myelin Sheath
The role of Nigella sativa against the Multiple Sclerosis
The metabolic imbalance in MS may be induced by oxidative stress or other associated factors, which gradually causes inflammation by increasing the expression of several pro-inflammatory factors like transforming growth factor - beta, raises NO level and decrease the levels of antioxidants naturally present in the body.
The inflammatory lesions appeared due to these pathophysiological changes induces demethylation in the white matter of the CNS and causes myelin sheath destruction. Nigella sativa and its active ingredient Thymoquinone have potent anti-inflammatory and antioxidant property.
Anti-inflammatory effect of N. sativa able to reduce the inflammation of the CNS by prominently reducing the pro-inflammatory mediators, including cytokines, TNF-alpha, NO levels in the brain.
Reactive oxygen species (ROS) build-up causes activation of astrocytes and microglia/macrophages, which is also responsible for the autoimmune inflammatory attack in MS and causes lesion formation in the nerve tissue and destruction of oligodendrocytes.
N. sativa treatment can decrease the number of reactive astrocytes and proliferated microglial cells due to its strong anti-oxidant property. Therefore, this herbal medicine is specifically beneficial for the neurodegenerative condition.
Reactive astrocytes and proliferated microglial cells numbers are markedly increased in Multiple Sclerosis and provide the neurodegenerative effect. The neuroprotective effect of Nigella sativa has the potential to decrease the number of reactive astrocytes and proliferated microglial cells. N. sativa prevents the relapse of MS condition or delays the symptomatic progression in MS patients by inhibiting astrocytic and microglial proliferation.
Oxidative stress decreases the scope of remethylation by reducing the level of malondialdehyde in the brain. The antioxidant property of Nigella sativa increase the scope of remethylation, however, it may not prevent dropping of malondialdehyde level in the brain.
High level of the astrocytes for TGF-β1 is expected to be the main culprit of histopathological changes in the nervous system that occur in Multiple Sclerosis condition. But the anti-inflammatory property of Nigella sativa can able to decrease the expression of astrocytes for TGF-β1 and control histopathological changes in the nervous system induced in Multiple Sclerosis condition. Therefore, Nigella sativa can protect and treat nervous system damaged due to Multiple Sclerosis. [3]
The metabolic imbalance in MS may be induced by oxidative stress or other associated factors, which gradually causes inflammation by increasing the expression of several pro-inflammatory factors like transforming growth factor - beta, raises NO level and decrease the levels of antioxidants naturally present in the body.
The inflammatory lesions appeared due to these pathophysiological changes induces demethylation in the white matter of the CNS and causes myelin sheath destruction. Nigella sativa and its active ingredient Thymoquinone have potent anti-inflammatory and antioxidant property.
Anti-inflammatory effect of N. sativa able to reduce the inflammation of the CNS by prominently reducing the pro-inflammatory mediators, including cytokines, TNF-alpha, NO levels in the brain.
Reactive oxygen species (ROS) build-up causes activation of astrocytes and microglia/macrophages, which is also responsible for the autoimmune inflammatory attack in MS and causes lesion formation in the nerve tissue and destruction of oligodendrocytes.
N. sativa treatment can decrease the number of reactive astrocytes and proliferated microglial cells due to its strong anti-oxidant property. Therefore, this herbal medicine is specifically beneficial for the neurodegenerative condition.
Reactive astrocytes and proliferated microglial cells numbers are markedly increased in Multiple Sclerosis and provide the neurodegenerative effect. The neuroprotective effect of Nigella sativa has the potential to decrease the number of reactive astrocytes and proliferated microglial cells. N. sativa prevents the relapse of MS condition or delays the symptomatic progression in MS patients by inhibiting astrocytic and microglial proliferation.
Oxidative stress decreases the scope of remethylation by reducing the level of malondialdehyde in the brain. The antioxidant property of Nigella sativa increase the scope of remethylation, however, it may not prevent dropping of malondialdehyde level in the brain.
High level of the astrocytes for TGF-β1 is expected to be the main culprit of histopathological changes in the nervous system that occur in Multiple Sclerosis condition. But the anti-inflammatory property of Nigella sativa can able to decrease the expression of astrocytes for TGF-β1 and control histopathological changes in the nervous system induced in Multiple Sclerosis condition. Therefore, Nigella sativa can protect and treat nervous system damaged due to Multiple Sclerosis. [3]
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MaeLoves974 9 months ago
Your video helped me reverse my ms symptoms in a couple of weeks
Myths and facts about the use of Nigella sativa in Multiple Sclerosis
Some of us may confuse about the application of Nigella sativa in Multiple Sclerosis because Nigella sativa is well established as an immune booster, so as per the medical recommendation, the immune booster should not be administered in Multiple Sclerosis. [4]
However, we have already discussed in above paragraph about the therapeutic effects of Nigella sativa in Multiple Sclerosis. There are several animal studies supporting the benefits of Nigella sativa in neurodegenerative conditions, including Multiple Sclerosis.
These studies not only explain how anti-inflammatory and anti-oxidant property of Nigella sativa prevent Multiple Sclerosis but also showed the scope of treating Multiple Sclerosis due to its remyelinating effect.
To remove further confusion, it is necessary to explain that Nigella sativa and its active ingredient thymoquinone have an immunomodulatory therapeutic effect, which is achieved by enhancing the T cell and natural killer cell-mediated immune responses.
Clinical researchers believe that Nigella sativa and its active ingredients have a role on antigen presenting cells in dendritic cells and improve the immunotherapeutic application in autoimmune disorders. [4]
It is also expected that N. sativa and thymoquinone modulate adaptive immune responses in cellular and humoral levels, and also has modulatory effects on Th1/Th2 paradigm, which controls inflammation in autoimmune disorders. [5, 6]
People mostly tried natural antioxidants supplements only in Multiple Sclerosis but the administration of Nigella sativa not only provide scavenging free radicals due to its potent anti-oxidant effect but also provide immunomodulatory therapeutic benefit, which is essential for treating neuronal inflammatory condition developed in Multiple Sclerosis. [6]
In addition, cytokines imbalance that occurs in Multiple Sclerosis is one of the primary cause of inflammation in the nervous system. A higher dose of Nigella sativa concentrated thymoquinone extract provides a more precise balance of cytokines in Th1/Th2. [7]
Some of us may confuse about the application of Nigella sativa in Multiple Sclerosis because Nigella sativa is well established as an immune booster, so as per the medical recommendation, the immune booster should not be administered in Multiple Sclerosis. [4]
However, we have already discussed in above paragraph about the therapeutic effects of Nigella sativa in Multiple Sclerosis. There are several animal studies supporting the benefits of Nigella sativa in neurodegenerative conditions, including Multiple Sclerosis.
These studies not only explain how anti-inflammatory and anti-oxidant property of Nigella sativa prevent Multiple Sclerosis but also showed the scope of treating Multiple Sclerosis due to its remyelinating effect.
To remove further confusion, it is necessary to explain that Nigella sativa and its active ingredient thymoquinone have an immunomodulatory therapeutic effect, which is achieved by enhancing the T cell and natural killer cell-mediated immune responses.
Clinical researchers believe that Nigella sativa and its active ingredients have a role on antigen presenting cells in dendritic cells and improve the immunotherapeutic application in autoimmune disorders. [4]
It is also expected that N. sativa and thymoquinone modulate adaptive immune responses in cellular and humoral levels, and also has modulatory effects on Th1/Th2 paradigm, which controls inflammation in autoimmune disorders. [5, 6]
People mostly tried natural antioxidants supplements only in Multiple Sclerosis but the administration of Nigella sativa not only provide scavenging free radicals due to its potent anti-oxidant effect but also provide immunomodulatory therapeutic benefit, which is essential for treating neuronal inflammatory condition developed in Multiple Sclerosis. [6]
In addition, cytokines imbalance that occurs in Multiple Sclerosis is one of the primary cause of inflammation in the nervous system. A higher dose of Nigella sativa concentrated thymoquinone extract provides a more precise balance of cytokines in Th1/Th2. [7]
Testimony of Nigella sativa Oil in MS-affected patient
A patient suffering from Multiple Sclerosis shared her medical history and reports before and after application of Nigella sativa oil.
She is suffering from chronic multiple sclerosis and frequent attacks, which interfere her daily activities and she unable to continue her study due to excessive fatigue condition.
Her clinician also suggested her to adjust her life to the symptoms of MS, as this disease is incurable. Fortunately, she attended a pharmacy exhibition and where she came to know about the facts of black seed oil also known as Nigella sativa.
Though she had a doubt that black seed oil intake boosts immunity, which may interfere the auto-immune nature of MS. But she started using black seed oil with a belief that it will rectify the immune system disorder, as black seed oil has the potentiality to react with immune system mediators.
She orally administered black seed oil with a cup of orange juice to mask the hard taste of the black seed oil. Within three days continuing this recipe, her study capacity has been increased and after 15 days all the MS symptoms, including fatigue, chronic numbness etc completely rid off.
She continued the therapy and conducted periodic MRIs (Magnetic Resonance Imaging). MRI reports showed the significant improvements in the nervous system due to the use of black seed oil. Black seed oil normalized the structure of the ventricular system, no lesion progression in the CNS and she survived without MS attacks for last 7.5 years.
This case history supports that Nigella sativa (Black seed) has the potency to treat and prevent MS attacks. [8]
A patient suffering from Multiple Sclerosis shared her medical history and reports before and after application of Nigella sativa oil.
She is suffering from chronic multiple sclerosis and frequent attacks, which interfere her daily activities and she unable to continue her study due to excessive fatigue condition.
Her clinician also suggested her to adjust her life to the symptoms of MS, as this disease is incurable. Fortunately, she attended a pharmacy exhibition and where she came to know about the facts of black seed oil also known as Nigella sativa.
Though she had a doubt that black seed oil intake boosts immunity, which may interfere the auto-immune nature of MS. But she started using black seed oil with a belief that it will rectify the immune system disorder, as black seed oil has the potentiality to react with immune system mediators.
She orally administered black seed oil with a cup of orange juice to mask the hard taste of the black seed oil. Within three days continuing this recipe, her study capacity has been increased and after 15 days all the MS symptoms, including fatigue, chronic numbness etc completely rid off.
She continued the therapy and conducted periodic MRIs (Magnetic Resonance Imaging). MRI reports showed the significant improvements in the nervous system due to the use of black seed oil. Black seed oil normalized the structure of the ventricular system, no lesion progression in the CNS and she survived without MS attacks for last 7.5 years.
This case history supports that Nigella sativa (Black seed) has the potency to treat and prevent MS attacks. [8]
The direction of Nigella sativa to treat MS
For treating multiple sclerosis, it is found from the testimony that daily intake of one tablespoon of Nigella sativa oil and a cup of orange juice is effective. [8]
Experts also suggest two teaspoons of Nigella sativa oil and raw honey is effective to treat Multiple sclerosis. [9]
Some Tips to reverse Multiple sclerosis naturally
For treating multiple sclerosis, it is found from the testimony that daily intake of one tablespoon of Nigella sativa oil and a cup of orange juice is effective. [8]
Experts also suggest two teaspoons of Nigella sativa oil and raw honey is effective to treat Multiple sclerosis. [9]
Some Tips to reverse Multiple sclerosis naturally
- A vegetarian diet is preferable to reverse Multiple Sclerosis.
- High-fat containing dietary items obtained from animal sources are strictly restricted for Multiple Sclerosis patient. Less than 20 g/day of fat consumption is allowable in the diet for Multiple Sclerosis.
- Omega-3 fatty acid rich diet is highly recommended. Fish oil supplements can be taken to fulfill the requirement of Omega-3 fatty acid in Multiple Sclerosis.
- Vegetable protein and dietary fiber obtained from various cereals, vitamin C-rich fruits are also required to add to the diet chart of the Multiple Sclerosis.
- Instead of other beverages, drink green tea. Green tea also provides anti-inflammatory and neuroprotective effects, which can improve Multiple Sclerosis. [10]
Which Black Seed Oil Do I Use?
I highly recommend this oil. This oil is and is the best oil in the whole world. I am so positive you will love my favorite oil too.
I highly recommend this oil. This oil is and is the best oil in the whole world. I am so positive you will love my favorite oil too.
REFERENCES
- Foroogh Namjooyan, Rahil Ghanavati, Nastaran Majdinasab, Shiva Jokari, Mohammad Janbozorgi. Uses of Complementary and Alternative Medicine in Multiple Sclerosis. J Tradit Complement Med. 2014 Jul-Sep; 4(3): 145–152. doi: 10.4103/2225-4110.136543. Online available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142451/
- Rahil Ghanavati, Foroogh Namjoyan, and Hosein Rezaee Zadeh. A Review of Possible Herbal Treatment in Multiple Sclerosis in Traditional Persian Medicine. Iran J Med Sci. 2016 May; 41(3 Suppl): S18. Online available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103523/
- Neveen A Noor, Heba M Fahmy, Faten F Mohammed, Anwar A Elsayed, Nasr M Radwan. Nigella sativa amliorates inflammation and demyelination in the experimental autoimmune encephalomyelitis-induced Wistar rats. Int J Clin Exp Pathol. 2015; 8(6): 6269–6286. Published online 2015 Jun 1. Online available https:/www.ncbi.nlm.nih.gov/pmc/articles/PMC4525838/
- Nigella Saliva Oil (Black Cumin). Online available at https://community.mssociety.org.uk/forum/everyday-living/nigella-saliva-oil-black-cumin
- Salem ML. Immunomodulatory and therapeutic properties of the Nigella sativa L. seed. Int Immunopharmacol. 2005 Dec;5(13-14):1749-70. Epub 2005 Jul 1. Online available at https://www.ncbi.nlm.nih.gov/pubmed/16275613
- Majdalawieh AF, Fayyad MW. Immunomodulatory and anti-inflammatory action of Nigella sativa and thymoquinone: A comprehensive review. Int Immunopharmacol. 2015 Sep;28(1):295-304. doi: 10.1016/j.intimp.2015.06.023. Epub 2015 Jun 26. Online available at https://www.ncbi.nlm.nih.gov/pubmed/26117430
- Gholamnezhad Z, Rafatpanah H, Sadeghnia HR, Boskabady MH. Immunomodulatory and cytotoxic effects of Nigella sativa and thymoquinone on rat splenocytes. Food Chem Toxicol. 2015 Dec;86:72-80. doi: 10.1016/j.fct.2015.08.028. Epub 2015 Sep 3. Online available at https://www.ncbi.nlm.nih.gov/pubmed/26342766
- MS cured by black seed oil and orange juice; Online available at https://www.curezone.org/forums/fm.asp?i=1843643
- Proper Dosage for Nigella Sativa. Online available at https://www.nigella--sativa.com/dosages.html
- Vijayshree Yadav, Lynne Shinto, Dennis Bourdette. Complementary and alternative medicine for the treatment of multiple sclerosis. Expert Rev Clin Immunol. Author manuscript; available in PMC 2011 Mar 1. Published in final edited form as: Expert Rev Clin Immunol. 2010 May; 6(3): 381–395. doi: 10.1586/eci.10.12 Online available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2901236/
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